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Remifentanil used as adjuvant in general anesthesia for spinal fusion does not exhibit acute opioid tolerance

BACKGROUND: Although acute tolerance to opioids, especially to remifentanil, has been demonstrated consistently in animal studies, the results of clinical trials in humans are controversial. The aim of this study was to determine whether intraoperative infusions of remifentanil used as an adjuvant i...

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Detalles Bibliográficos
Autores principales: Yeom, Jong Hoon, Kim, Kyoung Hun, Chon, Myong-Su, Byun, Jangwon, Cho, Sang Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427800/
https://www.ncbi.nlm.nih.gov/pubmed/22949975
http://dx.doi.org/10.4097/kjae.2012.63.2.103