Homogentisate 1,2 Dioxygenase is Expressed in Human Osteoarticular Cells: Implications in Alkaptonuria

Alkaptonuria (AKU) results from defective homogentisate1,2-dioxygenase (HGD), causing degenerative arthropathy. The deposition of ochronotic pigment in joints is so far attributed to homogentisic acid produced by the liver, circulating in the blood and accumulating locally. Human normal and AKU oste...

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Detalles Bibliográficos
Autores principales: Laschi, Marcella, Tinti, Laura, Braconi, Daniela, Millucci, Lia, Ghezzi, Lorenzo, Amato, Loredana, Selvi, Enrico, Spreafico, Adriano, Bernardini, Giulia, Santucci, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427883/
https://www.ncbi.nlm.nih.gov/pubmed/22105303
http://dx.doi.org/10.1002/jcp.24018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427883/
https://www.ncbi.nlm.nih.gov/pubmed/22105303
http://dx.doi.org/10.1002/jcp.24018

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