Daptomycin Resistance in Enterococci Is Associated with Distinct Alterations of Cell Membrane Phospholipid Content

BACKGROUND: The lipopeptide antibiotic, daptomycin (DAP) interacts with the bacterial cell membrane (CM). Development of DAP resistance during therapy in a clinical strain of Enterococcus faecalis was associated with mutations in genes encoding enzymes involved in cell envelope homeostasis and phosp...

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Detalles Bibliográficos
Autores principales: Mishra, Nagendra N., Bayer, Arnold S., Tran, Truc T., Shamoo, Yousif, Mileykovskaya, Eugenia, Dowhan, William, Guan, Ziqiang, Arias, Cesar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428275/
https://www.ncbi.nlm.nih.gov/pubmed/22952824
http://dx.doi.org/10.1371/journal.pone.0043958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428275/
https://www.ncbi.nlm.nih.gov/pubmed/22952824
http://dx.doi.org/10.1371/journal.pone.0043958

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