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Effects of Chronic Exposure to Arsenic and Estrogen on Epigenetic Regulatory Genes Expression and Epigenetic Code in Human Prostate Epithelial Cells

Chronic exposures to arsenic and estrogen are known risk factors for prostate cancer. Though the evidence suggests that exposure to arsenic or estrogens can disrupt normal DNA methylation patterns and histone modifications, the mechanisms by which these chemicals induce epigenetic changes are not fu...

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Detalles Bibliográficos
Autores principales: Treas, Justin N., Tyagi, Tulika, Singh, Kamaleshwar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428278/
https://www.ncbi.nlm.nih.gov/pubmed/22952798
http://dx.doi.org/10.1371/journal.pone.0043880