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KCa3.1 and TRPM7 Channels at the Uropod Regulate Migration of Activated Human T Cells

The migration of T lymphocytes is an essential part of the adaptive immune response as T cells circulate around the body to carry out immune surveillance. During the migration process T cells polarize, forming a leading edge at the cell front and a uropod at the cell rear. Our interest was in studyi...

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Detalles Bibliográficos
Autores principales: Kuras, Zerrin, Yun, Yeo-Heung, Chimote, Ameet A., Neumeier, Lisa, Conforti, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428288/
https://www.ncbi.nlm.nih.gov/pubmed/22952790
http://dx.doi.org/10.1371/journal.pone.0043859