Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) Slows Cancer Development but Increases Metastases in TRAMP Prostate Cancer Prone Mice

Macrophage inhibitory cytokine-1 (MIC-1/GDF15), a divergent member of the TGF-β superfamily, is over-expressed by many common cancers including those of the prostate (PCa) and its expression is linked to cancer outcome. We have evaluated the effect of MIC-1/GDF15 overexpression on PCa development an...

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Detalles Bibliográficos
Autores principales: Husaini, Yasmin, Qiu, Min Ru, Lockwood, Glen P., Luo, Xu Wei, Shang, Ping, Kuffner, Tamara, Tsai, Vicky Wang-Wei, Jiang, Lele, Russell, Pamela J., Brown, David A., Breit, Samuel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428289/
https://www.ncbi.nlm.nih.gov/pubmed/22952779
http://dx.doi.org/10.1371/journal.pone.0043833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428289/
https://www.ncbi.nlm.nih.gov/pubmed/22952779
http://dx.doi.org/10.1371/journal.pone.0043833

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