Cargando…

Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) Slows Cancer Development but Increases Metastases in TRAMP Prostate Cancer Prone Mice

Macrophage inhibitory cytokine-1 (MIC-1/GDF15), a divergent member of the TGF-β superfamily, is over-expressed by many common cancers including those of the prostate (PCa) and its expression is linked to cancer outcome. We have evaluated the effect of MIC-1/GDF15 overexpression on PCa development an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Husaini, Yasmin, Qiu, Min Ru, Lockwood, Glen P., Luo, Xu Wei, Shang, Ping, Kuffner, Tamara, Tsai, Vicky Wang-Wei, Jiang, Lele, Russell, Pamela J., Brown, David A., Breit, Samuel N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428289/ https://www.ncbi.nlm.nih.gov/pubmed/22952779 http://dx.doi.org/10.1371/journal.pone.0043833

Ejemplares similares

Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) Gene Deletion Promotes Cancer Growth in TRAMP Prostate Cancer Prone Mice
por: Husaini, Yasmin, et al.
Publicado: (2015)

TGF-b Superfamily Cytokine MIC-1/GDF15 Is a Physiological Appetite and Body Weight Regulator
por: Tsai, Vicky Wang-Wei, et al.
Publicado: (2013)

Anorexia/cachexia of chronic diseases: a role for the TGF-β family cytokine MIC-1/GDF15
por: Tsai, Vicky W. W., et al.
Publicado: (2012)

Macrophage Inhibitory Cytokine 1 (MIC-1/GDF15) Decreases Food Intake, Body Weight and Improves Glucose Tolerance in Mice on Normal & Obesogenic Diets
por: Macia, Laurence, et al.
Publicado: (2012)

The Anorectic Actions of the TGFβ Cytokine MIC-1/GDF15 Require an Intact Brainstem Area Postrema and Nucleus of the Solitary Tract
por: Tsai, Vicky Wang-Wei, et al.
Publicado: (2014)

MIC-1/GDF15 in Barrett's oesophagus and oesophageal adenocarcinoma
por: Fisher, O M, et al.
Publicado: (2015)

First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15
por: Low, Jac Kee, et al.
Publicado: (2017)

Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma
por: Wang, Xiaobing, et al.
Publicado: (2014)

Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI
por: Tsai, Vicky Wang-Wei, et al.
Publicado: (2015)

Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity
por: Husaini, Yasmin, et al.
Publicado: (2020)

Anorexia‐cachexia syndrome in hepatoma tumour‐bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC‐1/GDF15
por: Borner, Tito, et al.
Publicado: (2016)

Vamps & tramps /
por: Paglia, Camille, 1947-
Publicado: (2001)

The Tramp Journal
Publicado: (1892)

Circulating MIC-1/GDF15 is a complementary screening biomarker with CEA and correlates with liver metastasis and poor survival in colorectal cancer
por: Wang, Xiaobing, et al.
Publicado: (2017)

Genistein chemoprevention of prostate cancer in TRAMP mice
por: Wang, Jun, et al.
Publicado: (2007)

GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson’s Disease and Lewy Body Dementia
por: Maetzler, Walter, et al.
Publicado: (2016)

Increased serum levels of MIC1/GDF15 correlated with bone erosion in spondyloarthritis: A pilot study
por: Song, Yingyu, et al.
Publicado: (2018)

CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis
por: Salao, Kanin, et al.
Publicado: (2016)

β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model
por: Moran-Jones, Kim, et al.
Publicado: (2012)

Quercetin–Resveratrol Combination for Prostate Cancer Management in TRAMP Mice
por: Singh, Chandra K., et al.
Publicado: (2020)

MIC1 and MIC3: partners in invasion
por: Van Epps, Heather L.
Publicado: (2005)

Systemic alkalinisation delays prostate cancer cell progression in TRAMP mice
por: Astigiano, Simonetta, et al.
Publicado: (2017)

Glipizide suppresses prostate cancer progression in the TRAMP model by inhibiting angiogenesis
por: Qi, Cuiling, et al.
Publicado: (2016)

GDF15(MIC1) H6D Polymorphism Does Not Influence Cardiovascular Disease in a Latin American Population with Rheumatoid Arthritis
por: Amaya-Amaya, Jenny, et al.
Publicado: (2015)

Substrate specificity of the TRAMP nuclear surveillance complexes
por: Delan-Forino, Clémentine, et al.
Publicado: (2020)

Nrf2 Expression Is Regulated by Epigenetic Mechanisms in Prostate Cancer of TRAMP Mice
por: Yu, Siwang, et al.
Publicado: (2010)

Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer
por: Skipworth, R J E, et al.
Publicado: (2010)

Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues
por: Nakamura, T, et al.
Publicado: (2003)

Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice
por: Opoku-Acheampong, Alexander B., et al.
Publicado: (2013)

Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer
por: Gao, Xiaohua, et al.
Publicado: (2011)

GDF11 slows excitatory neuronal senescence and brain ageing by repressing p21
por: Wang, Di-Xian, et al.
Publicado: (2023)

Tumor Cell-Derived Exosomes from the Prostate Cancer Cell Line TRAMP-C1 Impair Osteoclast Formation and Differentiation
por: Karlsson, Terese, et al.
Publicado: (2016)

Therapeutic ISCOMATRIX™ adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer
por: Barr, Adele M., et al.
Publicado: (2020)

Evaluations of CRC2631 toxicity, tumor colonization, and genetic stability in the TRAMP prostate cancer model
por: Kazmierczak, Robert A., et al.
Publicado: (2020)

MRI to assess chemoprevention in transgenic adenocarcinoma of mouse prostate (TRAMP)
por: Arbab, Ali S, et al.
Publicado: (2011)

Growth and Progression of TRAMP Prostate Tumors in Relationship to Diet and Obesity
por: Bonorden, Melissa J. L., et al.
Publicado: (2012)

Circulatory MIC-1 as a Determinant of Prostate Cancer Racial Disparity
por: Karan, Dev, et al.
Publicado: (2020)

Phylogenetic evidence for independent origins of GDF1 and GDF3 genes in anurans and mammals
por: Opazo, Juan C., et al.
Publicado: (2018)

APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer
por: Søgaard, Caroline K., et al.
Publicado: (2018)

Aqueous metabolome of tissue‐specific conditional Pten‐knockout mouse prostate cancer and TRAMP neuroendocrine carcinoma
por: Kim, Sangyub, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0gp2t5ch8oqisl2ur44e9oed9a