Inhibition of EGFR-AKT Axis Results in the Suppression of Ovarian Tumors In Vitro and in Preclinical Mouse Model

Ovarian cancer is the leading cause of cancer related deaths in women. Genetic alterations including overexpression of EGFR play a crucial role in ovarian carcinogenesis. Here we evaluated the effect of phenethyl isothiocyanate (PEITC) in ovarian tumor cells in vitro and in vivo. Oral administration...

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Detalles Bibliográficos
Autores principales: Loganathan, Sivakumar, Kandala, Prabodh K., Gupta, Parul, Srivastava, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428303/
https://www.ncbi.nlm.nih.gov/pubmed/22952709
http://dx.doi.org/10.1371/journal.pone.0043577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428303/
https://www.ncbi.nlm.nih.gov/pubmed/22952709
http://dx.doi.org/10.1371/journal.pone.0043577

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