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Analysis of an Inactive Cyanobactin Biosynthetic Gene Cluster Leads to Discovery of New Natural Products from Strains of the Genus Microcystis

Cyanobactins are cyclic peptides assembled through the cleavage and modification of short precursor proteins. An inactive cyanobactin gene cluster has been described from the genome Microcystis aeruginosa NIES843. Here we report the discovery of active counterparts in strains of the genus Microcysti...

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Detalles Bibliográficos
Autores principales: Leikoski, Niina, Fewer, David P., Jokela, Jouni, Alakoski, Pirita, Wahlsten, Matti, Sivonen, Kaarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428304/
https://www.ncbi.nlm.nih.gov/pubmed/22952627
http://dx.doi.org/10.1371/journal.pone.0043002