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Rho-ROCK and Rac-PAK Signaling Pathways Have Opposing Effects on the Cell-to-Cell Spread of Marek's Disease Virus

Marek's Disease Virus (MDV) is an avian alpha-herpesvirus that only spreads from cell-to-cell in cell culture. While its cell-to-cell spread has been shown to be dependent on actin filament dynamics, the mechanisms regulating this spread remain largely unknown. Using a recombinant BAC20 virus e...

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Detalles Bibliográficos
Autores principales: Richerioux, Nicolas, Blondeau, Caroline, Wiedemann, Agnès, Rémy, Sylvie, Vautherot, Jean-François, Denesvre, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428312/
https://www.ncbi.nlm.nih.gov/pubmed/22952878
http://dx.doi.org/10.1371/journal.pone.0044072