Cargando…

Early Emergence and Selection of a SIV-LTR C/EBP Site Variant in SIV-Infected Macaques That Increases Virus Infectivity

CCAAT/enhancer binding protein (C/EBP)β, and C/EBP binding sites in the HIV/SIV- long terminal repeat (LTR) are crucial for regulating transcription and for IFNβ-mediated suppression of virus replication in macrophages, the predominant source of productive virus replication in the brain. We investig...

Descripción completa

Detalles Bibliográficos
Autores principales: Ravimohan, Shruthi, Gama, Lucio, Engle, Elizabeth L., Zink, M. Christine, Clements, Janice E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428313/
https://www.ncbi.nlm.nih.gov/pubmed/22952612
http://dx.doi.org/10.1371/journal.pone.0042801