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3D Multi-isotope Imaging Mass Spectrometry Reveals Penetration of (18)O-Trehalose in Mouse Sperm Nucleus

The prevalence of genetically engineered mice in medical research has led to ever increasing storage costs. Trehalose has a significant beneficial effect in preserving the developmental potential of mouse sperm following partial desiccation and storage at temperatures above freezing. Using multi-iso...

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Detalles Bibliográficos
Autores principales: Lechene, Claude P., Lee, Gloria Y., Poczatek, J. Collin, Toner, Mehmet, Biggers, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428319/
https://www.ncbi.nlm.nih.gov/pubmed/22952592
http://dx.doi.org/10.1371/journal.pone.0042267