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Kinetic Modelling of GlmU Reactions – Prioritization of Reaction for Therapeutic Application
Mycobacterium tuberculosis(Mtu), a successful pathogen, has developed resistance against the existing anti-tubercular drugs necessitating discovery of drugs with novel action. Enzymes involved in peptidoglycan biosynthesis are attractive targets for antibacterial drug discovery. The bifunctional enz...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428340/ https://www.ncbi.nlm.nih.gov/pubmed/22952829 http://dx.doi.org/10.1371/journal.pone.0043969 |