Hypoxia-Inducible Factor-1α Regulates Chemotactic Migration of Pancreatic Ductal Adenocarcinoma Cells through Directly Transactivating the CX3CR1 Gene

CX3CR1 is an important chemokine receptor and regulates the chemotactic migration of pancreatic ductal adenocarcinoma (PDAC) cells. Up to now, its regulatory mechanism remains largely undefined. Here, we report that hypoxia upregulates the expression of CX3CR1 in pancreatic cancer cells. When hypoxi...

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Detalles Bibliográficos
Autores principales: Zhao, Tiansuo, Gao, Song, Wang, Xiuchao, Liu, Jingcheng, Duan, Yitao, Yuan, Zhanna, Sheng, Jun, Li, Shasha, Wang, Feng, Yu, Ming, Ren, He, Hao, Jihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428361/
https://www.ncbi.nlm.nih.gov/pubmed/22952674
http://dx.doi.org/10.1371/journal.pone.0043399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428361/
https://www.ncbi.nlm.nih.gov/pubmed/22952674
http://dx.doi.org/10.1371/journal.pone.0043399

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