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Sepsis-Induced Cardiac Mitochondrial Dysfunction Involves Altered Mitochondrial-Localization of Tyrosine Kinase Src and Tyrosine Phosphatase SHP2

Our previous research demonstrated that sepsis produces mitochondrial dysfunction with increased mitochondrial oxidative stress in the heart. The present study investigated the role of mitochondria-localized signaling molecules, tyrosine kinase Src and tyrosine phosphatase SHP2, in sepsis-induced ca...

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Detalles Bibliográficos
Autores principales: Zang, Qun S., Martinez, Bobbie, Yao, Xiao, Maass, David L., Ma, Lisha, Wolf, Steven E., Minei, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428365/
https://www.ncbi.nlm.nih.gov/pubmed/22952679
http://dx.doi.org/10.1371/journal.pone.0043424