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Sepsis-Induced Cardiac Mitochondrial Dysfunction Involves Altered Mitochondrial-Localization of Tyrosine Kinase Src and Tyrosine Phosphatase SHP2
Our previous research demonstrated that sepsis produces mitochondrial dysfunction with increased mitochondrial oxidative stress in the heart. The present study investigated the role of mitochondria-localized signaling molecules, tyrosine kinase Src and tyrosine phosphatase SHP2, in sepsis-induced ca...
Autores principales: | Zang, Qun S., Martinez, Bobbie, Yao, Xiao, Maass, David L., Ma, Lisha, Wolf, Steven E., Minei, Joseph P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428365/ https://www.ncbi.nlm.nih.gov/pubmed/22952679 http://dx.doi.org/10.1371/journal.pone.0043424 |
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