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Intracerebroventricular Injection of Metformin Induces Anorexia in Rats
BACKGROUND: Metformin, an oral biguanide insulin-sensitizing agent, is well known to decrease appetite. Although there is evidence that metformin could affect the brain directly, the exact mechanism is not yet known. METHODS: To evaluate whether metformin induces anorexia via the hypothalamus, vario...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428418/ https://www.ncbi.nlm.nih.gov/pubmed/22950061 http://dx.doi.org/10.4093/dmj.2012.36.4.293 |