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The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy
More than 15 years ago the serial engagement model was proposed as an attempt to solve the low affinity/high sensitivity paradox of TCR antigen recognition. Since then, the model has undergone ups and downs marked by the technical and conceptual advancements made in the field of T lymphocyte activat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428561/ https://www.ncbi.nlm.nih.gov/pubmed/22973273 http://dx.doi.org/10.3389/fimmu.2012.00272 |