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Characterization of the Gene Expression Profile of Human Hippocampus in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis

One of the main putative causes of therapy refractory epilepsy in mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis is the overexpression of multidrug transporters (MDTs) at the blood-brain barrier (BBB). It steps up the removal of antiepileptic drugs (AEDs) out of the brain cells acro...

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Detalles Bibliográficos
Autores principales: Lachos, Julio, Zattoni, Michela, Wieser, Heinz-Gregor, Fritschy, Jean-Marc, Langmann, Thomas, Schmitz, Gerd, Errede, Mariella, Virgintino, Daniela, Yonekawa, Yasuhiro, Frei, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428621/
https://www.ncbi.nlm.nih.gov/pubmed/22937234
http://dx.doi.org/10.1155/2011/758407