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Model of Abnormal Chromophore-Protein Interaction for Е181К Rhodopsin Mutation: Computer Molecular Dynamics Study

The interaction of the 11-cis-retinal chromophore with the surrounding amino acid residues in the chromophore center of the rhodopsin protein has been investigated for the Е181К mutant form using molecular dynamics simulation. A comparative analysis of the arrangement of the amino acid residues in t...

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Detalles Bibliográficos
Autores principales: Feldman, Tatyana, Ostrovsky, Mikhail, Kholmurodov, Kholmirzo, Yasuoka, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428635/
https://www.ncbi.nlm.nih.gov/pubmed/22930661
http://dx.doi.org/10.2174/1874091X01206010094