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Hybridization and amplification rate correction for affymetrix SNP arrays
BACKGROUND: Copy number variation (CNV) is essential to understand the pathology of many complex diseases at the DNA level. Affymetrix SNP arrays, which are widely used for CNV studies, significantly depend on accurate copy number (CN) estimation. Nevertheless, CN estimation may be biased by several...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428662/ https://www.ncbi.nlm.nih.gov/pubmed/22691279 http://dx.doi.org/10.1186/1755-8794-5-24 |