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Hybridization and amplification rate correction for affymetrix SNP arrays

BACKGROUND: Copy number variation (CNV) is essential to understand the pathology of many complex diseases at the DNA level. Affymetrix SNP arrays, which are widely used for CNV studies, significantly depend on accurate copy number (CN) estimation. Nevertheless, CN estimation may be biased by several...

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Detalles Bibliográficos
Autores principales: Wang, Quan, Peng, Peichao, Qian, Minping, Wan, Lin, Deng, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428662/
https://www.ncbi.nlm.nih.gov/pubmed/22691279
http://dx.doi.org/10.1186/1755-8794-5-24

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