Designed, Synthetically Accessible Bryostatin Analogues Potently Induce Activation of Latent HIV Reservoirs in vitro

Bryostatin is a unique lead in the development of potentially transformative therapies for cancer, Alzheimer’s disease, and the eradication of HIV/AIDS. However, the clinical use of bryostatin has been hampered by its limited supply, difficulties in accessing clinically-relevant derivatives, and sid...

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Detalles Bibliográficos
Autores principales: DeChristopher, Brian A., Loy, Brian A., Marsden, Matthew D., Schrier, Adam J., Zack, Jerome A., Wender, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428736/
https://www.ncbi.nlm.nih.gov/pubmed/22914190
http://dx.doi.org/10.1038/nchem.1395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428736/
https://www.ncbi.nlm.nih.gov/pubmed/22914190
http://dx.doi.org/10.1038/nchem.1395

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