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Optogenetic silencing strategies differ in their effects on inhibitory synaptic transmission
Optogenetic silencing strategies using light-driven ion fluxes permit rapid and effective inhibition of neural activity. Using rodent hippocampal neurons we show that silencing activity with a chloride pump can increase the probability of synaptically-evoked spiking in the period following light-act...
Autores principales: | Raimondo, Joseph V., Kay, Louise, Ellender, Tommas J., Akerman, Colin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428858/ https://www.ncbi.nlm.nih.gov/pubmed/22729174 http://dx.doi.org/10.1038/nn.3143 |
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