Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

Endothelial Wnt/β-catenin signaling is necessary for angiogenesis of the central nervous system and blood–brain barrier (BBB) differentiation, but its relevance for glioma vascularization is unknown. In this study, we show that doxycycline-dependent Wnt1 expression in subcutaneous and intracranial m...

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Detalles Bibliográficos
Autores principales: Reis, Marco, Czupalla, Cathrin J., Ziegler, Nicole, Devraj, Kavi, Zinke, Jenny, Seidel, Sascha, Heck, Rosario, Thom, Sonja, Macas, Jadranka, Bockamp, Ernesto, Fruttiger, Marcus, Taketo, Makoto M., Dimmeler, Stefanie, Plate, Karl H., Liebner, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428944/
https://www.ncbi.nlm.nih.gov/pubmed/22908324
http://dx.doi.org/10.1084/jem.20111580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428944/
https://www.ncbi.nlm.nih.gov/pubmed/22908324
http://dx.doi.org/10.1084/jem.20111580

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