Cargando…

The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim

Developing B lymphocytes expressing defective or autoreactive pre-B or B cell receptors (BCRs) are eliminated by programmed cell death, but how the balance between death and survival signals is regulated to prevent immunodeficiency and autoimmunity remains incompletely understood. In this study, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Jurado, Sabine, Gleeson, Kimberly, O’Donnell, Kristy, Izon, David J., Walkley, Carl R., Strasser, Andreas, Tarlinton, David M., Heierhorst, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428950/
https://www.ncbi.nlm.nih.gov/pubmed/22891272
http://dx.doi.org/10.1084/jem.20120785