Cargando…
The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim
Developing B lymphocytes expressing defective or autoreactive pre-B or B cell receptors (BCRs) are eliminated by programmed cell death, but how the balance between death and survival signals is regulated to prevent immunodeficiency and autoimmunity remains incompletely understood. In this study, we...
Autores principales: | Jurado, Sabine, Gleeson, Kimberly, O’Donnell, Kristy, Izon, David J., Walkley, Carl R., Strasser, Andreas, Tarlinton, David M., Heierhorst, Jörg |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428950/ https://www.ncbi.nlm.nih.gov/pubmed/22891272 http://dx.doi.org/10.1084/jem.20120785 |
Ejemplares similares
-
The ASCIZ-DYNLL1 Axis Is Essential for TLR4-Mediated Antibody Responses and NF-κB Pathway Activation
por: Liu, Rui, et al.
Publicado: (2021) -
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
por: Becker, Jordan R., et al.
Publicado: (2018) -
ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress
por: Liu, Rui, et al.
Publicado: (2017) -
Dual Functions of ASCIZ in the DNA Base Damage Response and Pulmonary Organogenesis
por: Jurado, Sabine, et al.
Publicado: (2010) -
Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner
por: Liu, Rui, et al.
Publicado: (2018)