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The endoplasmic reticulum stress response in aging and age-related diseases

The endoplasmic reticulum(ER) is a multifunctional organelle within which protein folding, lipid biosynthesis, and calcium storage occurs. Perturbations such as energy or nutrient depletion, disturbances in calcium or redox status that disrupt ER homeostasis lead to the misfolding of proteins, ER st...

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Detalles Bibliográficos
Autores principales: Brown, Marishka K., Naidoo, Nirinjini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429039/
https://www.ncbi.nlm.nih.gov/pubmed/22934019
http://dx.doi.org/10.3389/fphys.2012.00263