Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling

Diabetic heart disease is a distinct clinical entity that can progress to heart failure and sudden death. However, the mechanisms responsible for the alterations in excitation-contraction coupling leading to cardiac dysfunction during diabetes are not well known. Hyperglycemia, the landmark of diabe...

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Detalles Bibliográficos
Autores principales: Kranstuber, Allyson L., del Rio, Carlos, Biesiadecki, Brandon J., Hamlin, Robert L., Ottobre, Joseph, Gyorke, Sandor, Lacombe, Véronique A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429064/
https://www.ncbi.nlm.nih.gov/pubmed/22934044
http://dx.doi.org/10.3389/fphys.2012.00292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429064/
https://www.ncbi.nlm.nih.gov/pubmed/22934044
http://dx.doi.org/10.3389/fphys.2012.00292

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