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An extracellular mechanism that can explain the neurotoxic effects of α-synuclein aggregates in the brain
Neurodegenerative diseases, such as Parkinson's disease (PD), Alzheimer's disease (AD), and Dementia with Lewy bodies (DLB), display an accumulation of proteins including α-synuclein aggregates in cortical and subcortical regions of the brain. PD is a complex, progressive disease which inv...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429068/ https://www.ncbi.nlm.nih.gov/pubmed/22934048 http://dx.doi.org/10.3389/fphys.2012.00297 |