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Alzheimer's disease models and functional genomics—How many needles are there in the haystack?

Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) are complex human brain disorders that affect an increasing number of people worldwide. With the identification first of the proteins that aggregate in AD and FTLD brains and subsequently of pathogenic gene mutations that cau...

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Detalles Bibliográficos
Autores principales: Götz, Jürgen, Matamales, Miriam, Götz, Naeman N., Ittner, Lars M., Eckert, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429089/
https://www.ncbi.nlm.nih.gov/pubmed/22934069
http://dx.doi.org/10.3389/fphys.2012.00320