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Extrasynaptic Glutamate Receptor Activation as Cellular Bases for Dynamic Range Compression in Pyramidal Neurons

Repetitive synaptic stimulation overcomes the ability of astrocytic processes to clear glutamate from the extracellular space, allowing some dendritic segments to become submerged in a pool of glutamate, for a brief period of time. This dynamic arrangement activates extrasynaptic NMDA receptors loca...

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Detalles Bibliográficos
Autores principales: Oikonomou, Katerina D., Short, Shaina M., Rich, Matthew T., Antic, Srdjan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429100/
https://www.ncbi.nlm.nih.gov/pubmed/22934081
http://dx.doi.org/10.3389/fphys.2012.00334