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Period2 gene mutant mice show compromised insulin-mediated endothelial nitric oxide release and altered glucose homeostasis

Period2 (Per2) is an important component of the circadian clock. Mutation of this gene is associated with vascular endothelial dysfunction and altered glucose metabolism. The aim of this study is to further characterize whole body glucose homeostasis and endothelial nitric oxide (NO) production in r...

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Detalles Bibliográficos
Autores principales: Carvas, João M., Vukolic, Ana, Yepuri, Gautham, Xiong, Yuyan, Popp, Katja, Schmutz, Isabelle, Chappuis, Sylvie, Albrecht, Urs, Ming, Xiu-Fen, Montani, Jean-Pierre, Yang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429102/
https://www.ncbi.nlm.nih.gov/pubmed/22934083
http://dx.doi.org/10.3389/fphys.2012.00337