Pravastatin-induced improvement in coronary reactivity and circulating ATP and ADP levels in young adults with type 1 diabetes

Aims: Extracellular ATP and ADP regulate diverse inflammatory, prothrombotic and vasoactive responses in the vasculature. Statins have been shown to modulate their signaling pathways in vitro. We hypothesized that altered intravascular nucleotide turnover modulates vasodilation in patients with type...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiviniemi, Tuomas O., Yegutkin, Gennady G., Toikka, Jyri O., Paul, Subhadeep, Aittokallio, Tero, Janatuinen, Tuula, Knuuti, Juhani, Rönnemaa, Tapani, Koskenvuo, Juha W., Hartiala, Jaakko J., Jalkanen, Sirpa, Raitakari, Olli T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429103/
https://www.ncbi.nlm.nih.gov/pubmed/22934084
http://dx.doi.org/10.3389/fphys.2012.00338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429103/
https://www.ncbi.nlm.nih.gov/pubmed/22934084
http://dx.doi.org/10.3389/fphys.2012.00338

Ejemplares similares