Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer

BACKGROUND: The CD44 transmembrane glycoproteins play multifaceted roles in tumor progression and metastasis. CD44 expression has also been associated with stem-like breast cancer cells. Hypoxia commonly occurs in tumors and is a major cause of radiation and chemo-resistance. Hypoxia is known to inh...

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Detalles Bibliográficos
Autores principales: Krishnamachary, Balaji, Penet, Marie-France, Nimmagadda, Sridhar, Mironchik, Yelena, Raman, Venu, Solaiyappan, Meiyappan, Semenza, Gregg L., Pomper, Martin G., Bhujwalla, Zaver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429433/
https://www.ncbi.nlm.nih.gov/pubmed/22937154
http://dx.doi.org/10.1371/journal.pone.0044078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429433/
https://www.ncbi.nlm.nih.gov/pubmed/22937154
http://dx.doi.org/10.1371/journal.pone.0044078

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