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YY1-Binding Sites Provide Central Switch Functions in the PARP-1 Gene Expression Network

Evidence is presented for the involvement of the interplay between transcription factor Yin Yang 1 (YY1) and poly(ADP-ribose) polymerase-1 (PARP-1) in the regulation of mouse PARP-1 gene (muPARP-1) promoter activity. We identified potential YY1 binding motifs (BM) at seven positions in the muPARP-1...

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Detalles Bibliográficos
Autores principales: Doetsch, Martina, Gluch, Angela, Poznanović, Goran, Bode, Juergen, Vidaković, Melita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429435/
https://www.ncbi.nlm.nih.gov/pubmed/22937159
http://dx.doi.org/10.1371/journal.pone.0044125