Elevating SOX2 Levels Deleteriously Affects the Growth of Medulloblastoma and Glioblastoma Cells

Medulloblastomas and glioblastomas are devastating tumors that respond poorly to treatment. These tumors have been shown to express SOX2 and overexpression of SOX2 has been correlated with poor prognosis. Although knockdown of SOX2 impairs the growth and tumorigenicity of brain tumor cells, it was u...

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Detalles Bibliográficos
Autores principales: Cox, Jesse L., Wilder, Phillip J., Desler, Michelle, Rizzino, Angie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429438/
https://www.ncbi.nlm.nih.gov/pubmed/22937156
http://dx.doi.org/10.1371/journal.pone.0044087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429438/
https://www.ncbi.nlm.nih.gov/pubmed/22937156
http://dx.doi.org/10.1371/journal.pone.0044087

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