Influence of Target Concentration and Background Binding on In Vitro Selection of Affinity Reagents

Nucleic acid-based aptamers possess many useful features that make them a promising alternative to antibodies and other affinity reagents, including well-established chemical synthesis, reversible folding, thermal stability and low cost. However, the selection process typically used to generate apta...

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Detalles Bibliográficos
Autores principales: Wang, Jinpeng, Rudzinski, Joseph F., Gong, Qiang, Soh, H. Tom, Atzberger, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429449/
https://www.ncbi.nlm.nih.gov/pubmed/22952815
http://dx.doi.org/10.1371/journal.pone.0043940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429449/
https://www.ncbi.nlm.nih.gov/pubmed/22952815
http://dx.doi.org/10.1371/journal.pone.0043940

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