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Influence of Target Concentration and Background Binding on In Vitro Selection of Affinity Reagents
Nucleic acid-based aptamers possess many useful features that make them a promising alternative to antibodies and other affinity reagents, including well-established chemical synthesis, reversible folding, thermal stability and low cost. However, the selection process typically used to generate apta...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429449/ https://www.ncbi.nlm.nih.gov/pubmed/22952815 http://dx.doi.org/10.1371/journal.pone.0043940 |