Identification of Thalidomide-Specific Transcriptomics and Proteomics Signatures during Differentiation of Human Embryonic Stem Cells

Embryonic development can be partially recapitulated in vitro by differentiating human embryonic stem cells (hESCs). Thalidomide is a developmental toxicant in vivo and acts in a species-dependent manner. Besides its therapeutic value, thalidomide also serves as a prototypical model to study teratog...

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Detalles Bibliográficos
Autores principales: Meganathan, Kesavan, Jagtap, Smita, Wagh, Vilas, Winkler, Johannes, Gaspar, John Antonydas, Hildebrand, Diana, Trusch, Maria, Lehmann, Karola, Hescheler, Jürgen, Schlüter, Hartmut, Sachinidis, Agapios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429450/
https://www.ncbi.nlm.nih.gov/pubmed/22952932
http://dx.doi.org/10.1371/journal.pone.0044228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429450/
https://www.ncbi.nlm.nih.gov/pubmed/22952932
http://dx.doi.org/10.1371/journal.pone.0044228

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