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Fatigue and Muscle Atrophy in a Mouse Model of Myasthenia Gravis Is Paralleled by Loss of Sarcolemmal nNOS

Myasthenia Gravis (MG) patients suffer from chronic fatigue of skeletal muscles, even after initiation of proper immunosuppressive medication. Since the localization of neuronal nitric oxide synthase (nNOS) at the muscle membrane is important for sustained muscle contraction, we here study the local...

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Detalles Bibliográficos
Autores principales: Meinen, Sarina, Lin, Shuo, Rüegg, Markus A., Punga, Anna Rostedt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429452/
https://www.ncbi.nlm.nih.gov/pubmed/22952904
http://dx.doi.org/10.1371/journal.pone.0044148