Analysis of the Role of Igf2 in Adrenal Tumour Development in Transgenic Mouse Models

Adrenal cortical carcinomas (ACC) are rare but aggressive tumours associated with poor prognosis. The two most frequent alterations in ACC in patients are overexpression of the growth factor IGF2 and constitutive activation of Wnt/β-catenin signalling. Using a transgenic mouse model, we have previou...

Descripción completa

Detalles Bibliográficos
Autores principales: Drelon, Coralie, Berthon, Annabel, Ragazzon, Bruno, Tissier, Frédérique, Bandiera, Roberto, Sahut-Barnola, Isabelle, de Joussineau, Cyrille, Batisse-Lignier, Marie, Lefrançois-Martinez, Anne-Marie, Bertherat, Jérôme, Martinez, Antoine, Val, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429465/
https://www.ncbi.nlm.nih.gov/pubmed/22952916
http://dx.doi.org/10.1371/journal.pone.0044171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429465/
https://www.ncbi.nlm.nih.gov/pubmed/22952916
http://dx.doi.org/10.1371/journal.pone.0044171

Ejemplares similares