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Adaptive Ridge Regression for Rare Variant Detection

It is widely believed that both common and rare variants contribute to the risks of common diseases or complex traits and the cumulative effects of multiple rare variants can explain a significant proportion of trait variances. Advances in high-throughput DNA sequencing technologies allow us to geno...

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Detalles Bibliográficos
Autores principales: Zhan, Haimao, Xu, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429469/
https://www.ncbi.nlm.nih.gov/pubmed/22952918
http://dx.doi.org/10.1371/journal.pone.0044173