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Adaptive Ridge Regression for Rare Variant Detection
It is widely believed that both common and rare variants contribute to the risks of common diseases or complex traits and the cumulative effects of multiple rare variants can explain a significant proportion of trait variances. Advances in high-throughput DNA sequencing technologies allow us to geno...
Autores principales: | Zhan, Haimao, Xu, Shizhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429469/ https://www.ncbi.nlm.nih.gov/pubmed/22952918 http://dx.doi.org/10.1371/journal.pone.0044173 |
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