Human Apolipoprotein A-I Natural Variants: Molecular Mechanisms Underlying Amyloidogenic Propensity

Human apolipoprotein A-I (apoA-I)-derived amyloidosis can present with either wild-type (Wt) protein deposits in atherosclerotic plaques or as a hereditary form in which apoA-I variants deposit causing multiple organ failure. More than 15 single amino acid replacement amyloidogenic apoA-I variants h...

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Detalles Bibliográficos
Autores principales: Ramella, Nahuel A., Schinella, Guillermo R., Ferreira, Sergio T., Prieto, Eduardo D., Vela, María E., Ríos, José Luis, Tricerri, M. Alejandra, Rimoldi, Omar J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429494/
https://www.ncbi.nlm.nih.gov/pubmed/22952757
http://dx.doi.org/10.1371/journal.pone.0043755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429494/
https://www.ncbi.nlm.nih.gov/pubmed/22952757
http://dx.doi.org/10.1371/journal.pone.0043755

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