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Potent Adjuvanticity of a Pure TLR7-Agonistic Imidazoquinoline Dendrimer

Engagement of toll-like receptors (TLRs) serve to link innate immune responses with adaptive immunity and can be exploited as powerful vaccine adjuvants for eliciting both primary and anamnestic immune responses. TLR7 agonists are highly immunostimulatory without inducing dominant proinflammatory cy...

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Detalles Bibliográficos
Autores principales: Shukla, Nikunj M., Salunke, Deepak B., Balakrishna, Rajalakshmi, Mutz, Cole A., Malladi, Subbalakshmi S., David, Sunil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429503/
https://www.ncbi.nlm.nih.gov/pubmed/22952720
http://dx.doi.org/10.1371/journal.pone.0043612