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Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can’t beat them, join them

The proopiomelanocortin (Pomc) gene encodes a prepropeptide with essential functions in the response to stress and energy balance, which is expressed in the pituitary and hypothalamus of vertebrate animals. Neuronal expression of Pomc is controlled by two distal enhancers named nPE1 and nPE2. Using...

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Detalles Bibliográficos
Autores principales: Franchini, Lucia F., de Souza, Flavio S.J., Low, Malcolm J., Rubinstein, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429518/
https://www.ncbi.nlm.nih.gov/pubmed/22934245
http://dx.doi.org/10.4161/mge.20267