Targeting pre-miRNA by Peptide Nucleic Acids: A new strategy to interfere in the miRNA maturation

PNAs conjugated to carrier peptides have been employed for the targeting of miRNA precursor, with the aim to develop molecules able to interfere in the pre-miRNA processing. The capability of the molecules to bind pre-miRNA has been tested in vitro by fluorescence assayes on Thiazole Orange labeled...

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Detalles Bibliográficos
Autores principales: Avitabile, Concetta, Saviano, Michele, D'Andrea, Luca, Bianchi, Nicoletta, Fabbri, Enrica, Brognara, Eleonora, Gambari, Roberto, Romanelli, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429535/
https://www.ncbi.nlm.nih.gov/pubmed/22699795
http://dx.doi.org/10.4161/adna.20911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429535/
https://www.ncbi.nlm.nih.gov/pubmed/22699795
http://dx.doi.org/10.4161/adna.20911

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