Macroautophagy is deregulated in murine and human lupus T lymphocytes

Macroautophagy was recently shown to regulate both lymphocyte biology and innate immunity. In this study we sought to determine whether a deregulation of autophagy was linked to the development of autoimmunity. Genome-wide association studies have pointed out nucleotide polymorphisms that can be ass...

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Detalles Bibliográficos
Autores principales: Gros, Frédéric, Arnold, Johan, Page, Nicolas, Décossas, Marion, Korganow, Anne-Sophie, Martin, Thierry, Muller, Sylviane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429547/
https://www.ncbi.nlm.nih.gov/pubmed/22522825
http://dx.doi.org/10.4161/auto.20275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429547/
https://www.ncbi.nlm.nih.gov/pubmed/22522825
http://dx.doi.org/10.4161/auto.20275

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