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Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila

Autophagy delivers cytoplasmic material for lysosomal degradation in eukaryotic cells. Starvation induces high levels of autophagy to promote survival in the lack of nutrients. We compared genome-wide transcriptional profiles of fed and starved control, autophagy-deficient Atg7 and Atg1 null mutant...

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Detalles Bibliográficos
Autores principales: Érdi, Balázs, Nagy, Péter, Zvara, Ágnes, Varga, Ágnes, Pircs, Karolina, Ménesi, Dalma, Puskás, László G., Juhász, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429548/
https://www.ncbi.nlm.nih.gov/pubmed/22562043
http://dx.doi.org/10.4161/auto.20069